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1

Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model

Hanna Shevalye, Roman Stavniichuk, Weizheng Xu, Jie Zhang, Sergey Lupachyk, Yury Maksimchyk, Viktor R. Drel, Elizabeth Z. Floyd, Barbara Slusher, Irina G. Obrosova

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 499 KB

english, 2010

2

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice

Viktor R. Drel, Pal Pacher, Igor Vareniuk, Ivan Pavlov, Olga Ilnytska, Valeriy V. Lyzogubov, Jyoti Tibrewala, John T. Groves, Irina G. Obrosova

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.23 MB

english, 2007

3

Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells

Viktor R. Drel, Pal Pacher, Martin J. Stevens, Irina G. Obrosova

Journal:

Free Radical Biology and Medicine

Year:

2006

Language:

english

File:

PDF, 852 KB

english, 2006

4

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy

Irina G. Obrosova, Weizheng Xu, Valeriy V. Lyzogubov, Olga Ilnytska, Nazar Mashtalir, Igor Vareniuk, Ivan A. Pavlov, Jie Zhang, Barbara Slusher, Viktor R. Drel

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

5

Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies

Roman Stavniichuk, Viktor R. Drel, Hanna Shevalye, Igor Vareniuk, Martin J. Stevens, Jerry L. Nadler, Irina G. Obrosova

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

6

PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: Correlation with peripheral nerve function

Sergey Lupachyk, Hanna Shevalye, Yury Maksimchyk, Viktor R. Drel, Irina G. Obrosova

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

7

Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice

Igor Vareniuk, Ivan A. Pavlov, Viktor R. Drel, Valeriy V. Lyzogubov, Olga Ilnytska, Seth R. Bell, Jyoti Tibrewala, John T. Groves, Irina G. Obrosova

Journal:

Experimental Neurology

Year:

2007

Language:

english

File:

PDF, 2.02 MB

english, 2007

8

Different Roles of 12/15-Lipoxygenase in Diabetic Large and Small Fiber Peripheral and Autonomic Neuropathies

Irina G. Obrosova, Roman Stavniichuk, Viktor R. Drel, Hanna Shevalye, Igor Vareniuk, Jerry L. Nadler, Robert. E. Schmidt

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

9

Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation

Roman Stavniichuk, Viktor R. Drel, Hanna Shevalye, Yury Maksimchyk, Tamara M. Kuchmerovska, Jerry L. Nadler, Irina G. Obrosova

Journal:

Experimental Neurology

Year:

2011

Language:

english

File:

PDF, 680 KB

english, 2011

10

Protective effects of polyphenolics in red wine on diabetes associated oxidative/nitrative stress in streptozotocin-diabetic rats

Drel, Viktor R, Sybirna, Nataliya

Journal:

Cell Biology International

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

11

Poly(Adenosine 5′-Diphosphate-Ribose) Polymerase Inhibition Counteracts Multiple Manifestations of Experimental Type 1 Diabetic Nephropathy

Drel, Viktor R., Xu, Weizheng, Zhang, Jie, Pavlov, Ivan A., Shevalye, Hanna, Slusher, Barbara, Obrosova, Irina G.

Journal:

Year:

2009

Language:

english

File:

PDF, 562 KB

english, 2009

12

New Therapeutic and Biomarker Discovery for Peripheral Diabetic Neuropathy: PARP Inhibitor, Nitrotyrosine, and Tumor Necrosis Factor-α

Drel, Viktor R., Lupachyk, Sergey, Shevalye, Hanna, Vareniuk, Igor, Xu, Weizheng, Zhang, Jie, Delamere, Nicholas A., Shahidullah, Mohammad, Slusher, Barbara, Obrosova, Irina G.

Journal:

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

13

Pathophysiology of gadolinium-associated systemic fibrosis

Wagner, Brent, Drel, Viktor, Gorin, Yves

Journal:

AJP: Renal Physiology

Year:

2016

Language:

english

File:

PDF, 1.94 MB

english, 2016

14

Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis

Drel, Viktor, Pacher, Pal, Ali, Tayyeba, Shin, Jeho, Julius, Ulrich, El-Remessy, Azza, Obrosova, Irina

Journal:

International Journal of Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 409 KB

english, 2008

15

Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes

Drel, Viktor, Pacher, Pal, Vareniuk, Igor, Pavlov, Ivan, Ilnytska, Olga, Lyzogubov, Valeriy, Bell, Seth, Groves, John, Obrosova, Irina

Journal:

International Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 546 KB

english, 2007

16

New Therapeutic and Biomarker Discovery for Peripheral Diabetic Neuropathy: PARP Inhibitor, Nitrotyrosine, and Tumor Necrosis Factor-α

Drel, Viktor R., Lupachyk, Sergey, Shevalye, Hanna, Vareniuk, Igor, Xu, Weizheng, Zhang, Jie, Delamere, Nicholas A., Shahidullah, Mohammad, Slusher, Barbara, Obrosova, Irina G.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

File:

PDF, 35 KB

2010

17

Poly(ADP-Ribose)Polymerase Inhibition Counteracts Cataract Formation and Early Retinal Changes in Streptozotocin-Diabetic Rats

Drel, Viktor R., Xu, Weizheng, Zhang, Jie, Kador, Peter F., Ali, Tayyeba K., Shin, Jeho, Julius, Ulrich, Slusher, Barbara, El-Remessy, Azza B., Obrosova, Irina G.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2009

Language:

english

File:

PDF, 2.20 MB

english, 2009

18

New Therapeutic and Biomarker Discovery for Peripheral Diabetic Neuropathy: PARP Inhibitor, Nitrotyrosine, and Tumor Necrosis Factor-α

Drel, Viktor R., Lupachyk, Sergey, Shevalye, Hanna, Vareniuk, Igor, Xu, Weizheng, Zhang, Jie, Delamere, Nicholas A., Shahidullah, Mohammad, Slusher, Barbara, Obrosova, Irina G.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 35 KB

english, 2010

19

Nephrogenic Systemic Fibrosis Is Mediated by Myeloid C-C Chemokine Receptor 2

Do, Catherine, Drel, Viktor, Tan, Chunyan, Lee, Doug, Wagner, Brent

Journal:

The Journal of Investigative Dermatology

Year:

2019

Language:

english

File:

PDF, 4.18 MB

english, 2019